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“Young people without known risk factors, aside from obesity, have died shortly after initiating sibutramine therapy,” states the review from the FDA’s office of surveillance, which monitors adverse events reported with drugs. Meridia users is 44, so any adverse events reported with the drug would be among relatively young patients. Davies said the North Chicago based company will use Wednesday’s meeting to suggest “risk management measures to ensure that the drug is used in the appropriate patient population.”.

Carbohydrate replacement is necessary in events lasting longer than 90 minutes and may even be beneficial during high intensity exercise of shorter duration. This applies to both continuous events like cycling, running, and hiking, and sports with intermittent activity like soccer and weight training. Under these conditions, consuming carbohydrates during exercise increases both the time and the intensity the athlete is able to exercise before becoming exhausted.