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They were working with three different types of mice with different levels of glial cell line derived neurotrophic factor (GDNF) which is a protein that helps in kidney development. Nephron number,pastillas para adelgazar rapido fruta planta, mean arterial pressure and renal function was measured before and after a high salt diet. The first type of mouse had normal GDNF function (WT), the second type had 2 kidneys but 25% fewer nephrons (HET2K), the third type had 1 kidney and 65% fewer nephrons (HET1K) as compared to normal..