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“The anticonvulsant in both Contrave and Qnexa is a new variation on the theme of tweaking brain pathways to adjust appetite but does not appear to be more than a minor innovation to me, and one of questionable utility,green coffee 800,” said Dr. David L. Katz, associate professor adjunct in public health practice at the Yale School of Public Health..

Material appearing in electronic databases after this point is therefore outside the scope of the review. Given the limited time and resources available for the review, it was necessary to restrict searches to the English language literature. Previous experience with similar reviews suggests that this restriction is unlikely to have had a significant impact on outcomes.