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The immune deficiency seen in starvation may result from diminished leptin secretion. Mice lacking the gene for leptin or its receptor show impairment of T cell function, and in laboratory studies leptin has induced a proliferative response in human CD4 lymphocytes. Elevation of leptin appears to be a risk factor for cardiovascular disease.

As a result, they are lower in fiber and protein nutrients that promote stabilized blood sugar levels, energy levels and appetite control. Sheila Dean, a registered dietitian at the Palm Harbor Center for Health and Healing in Florida, recommends a fiber rich diet based on whole foods for people with thyroid disease as a useful way to reach and maintain a healthy weight. Whole grains, such as brown rice, barley and quinoa, provide nutritious alternatives to refined grain products, such as enriched cereals, breads and pastas..